LETTERS TO THE EDITOR

LETTERS/COLUMNS: SEND LETTERS TO THE EDITOR FOR PUBLISHING TO FRONTPAGENEWS1@YAHOO.COM. PLEASE INCLUDE DAY/EVENING/ CELL NUMBER, HOME NUMBER, AND EMAIL. CONTACT VAN STONE: FRONTPAGENEWS1@YAHOO.COM OR (215) 821-9147 TO SUBMIT A REQUEST FOR ANY WRITER. PLEASE DO NOT CONTACT THE WRITER DIRECTLY! ALL APPEARANCE REQUEST WILL GO THROUGH THE MANAGING EDITOR'S OFFICE. COPYRIGHT: THE USE OF ANY SUBMISSIONS APPEARING ON THIS SITE FOR MONETARY GAINS IS STRICTLY PROHIBITED. TO LEARN MORE: PHILADELPHIA FRONT PAGE NEWS WWW.FPNNEWS.ORG. YOUR TOP STORIES OF THE DAY (215) 821-9147.

Monday, June 29, 2009

FDA weighs options to reduce painkiller overdoses

FDA weighs options to reduce painkiller overdoses

AP Photo
FILE - In this Dec. 12, 2007 file photo, Tylenol drugs are shown in the drug department at Costco in Mountain View, Calif. During a two-day meeting that started Monday June 29, 2009, the FDA is asking more than 35 experts what additional steps can be taken to reduce accidental overdose with the over-the-counter and prescription pain relievers.

ADELPHI, Md. (AP) -- The makers of Tylenol, Excedrin and other medications are trying to dissuade regulators from placing new restrictions on their popular painkillers, including possibly removing some of them from store shelves.

The Food and Drug Administration has assembled more than 35 experts to discuss ways to prevent overdose with acetaminophen - the pain-relieving, fever-reducing ingredient in Tylenol and dozens of other prescription and over-the-counter medications.

Despite years of educational campaigns and other federal actions, acetaminophen is the leading cause of liver failure in the U.S., sending 56,000 people to the emergency room annually, according to the FDA.

The agency on Monday asked its experts to consider a range of options: adding a "black box" warning label to the products, lowering the drug dosage in some products, or pulling certain types of medications off the market.

The drugs that could be pulled off shelves are combination medications, such as Procter & Gamble's NyQuil or Novartis' Theraflu, which combine acetaminophen with other ingredients that treat cough and runny nose.

The FDA says patients often pair them with a pure acetaminophen medication, like Tylenol, exposing themselves to unsafe levels of the drug.

But the industry group that represents Johnson & Johnson, Wyeth and other companies defended the products Monday, saying they pose a relatively small risk to patients.

Only 10 percent of deaths linked to acetaminophen medications involved over-the-counter combination cold medications, according to the Consumer Healthcare Products Association.

The majority of deaths were caused by either single-ingredient drugs or prescription strength combination drugs like Percocet, which combines oxycodone and acetaminophen.

"We believe there is a clear health benefit of over-the-counter combination products containing acetaminophen," said Linda Suydam, the group's president.

The FDA is not required to follow the advice of its panels, though it usually does. The panel vote is scheduled for Tuesday afternoon.

Manufacturers could lose hundreds of millions of dollars in sales if combination drugs are pulled from the market. Total sales of all acetaminophen drugs reached $2.6 billion last year, with 80 percent of the market comprised of over-the-counter products.

Tylenol-maker Johnson & Johnson also pushed back against a proposal to lower the maximum daily dose of acetaminophen, which is currently 4 grams daily, or eight pills of a medication like Extra Strength Tylenol.

While taking more than 4 grams per day can cause liver injury, J&J argued that taking the exact dose is proven to treat osteoarthritis pain.

J&J also warned panelists that any new restrictions on acetaminophen would force patients to switch to nonsteroidal anti-inflammatory drugs, which carry risks of gastrointestinal bleeding and sometimes fatal kidney injury.

"When switching occurs, the risk of death increases," said Dr. Kenneth Rothman, a consultant for J&J. According to figures from Rothman, a 30 percent switch away from acetaminophen would result in an additional 5,000 deaths per year.

Top-sellers in the anti-inflammatory drug market include Bayer AG's aspirin and Wyeth's Advil.

Executives from Wyeth scheduled a series of media briefings last week, arguing there's no evidence that the reduced use of acetaminophen would cause more negative side effects with their drug.

"There are major flaws in their arguments that are not born out in real world experience," said Dr. Paul Desjardins, a vice president with Wyeth.

Desjardins pointed out that the U.K. has put tighter safety measures in place for acetaminophen without causing increased problems with Advil and other nonsteroidal anti-inflammatory drugs.

For its part, the FDA has made clear it will not play king-maker in the market for over-the-counter medications. The agency says its only goal is to reduce liver injury, "not to decrease appropriate acetaminophen use or to drive people to use NSAIDS instead."

Van Stone Productions Inc. 501C3 Nonprofit Organization Informatioin (EIN) / Tax ID

Van Stone Productions Inc. 501C3 Nonprofit Organization Informatioin (EIN) / Tax ID
Click on the logo to learn about the non-profit status

BECOME OUR VLOGGER OF THE MONTH: VIDEO NEWS CONTENT PUBLISHED ON ANY TOPIC BELOW

Latest edition of Talk Live Philly With Van Stone

VAN STONE PERFORMANCE PROMOTION VIDEO AT WEST PHILADELPHIA HS 1999 - BELOW

FPN NEWS “TAKE TIME FOR WINNERS IN ANY COMMUNITY!”

Van Stones' Beautiful World Images -Latinamerica, South Asia, and USA Fashion and Beauty Collection

Van Stones' Beautiful World Images -Latinamerica, South Asia, and USA Fashion and Beauty Collection
Family Modeling -modelado de la familia

Van Stones' Beautiful World Images -Hermosas World Images Van Stones

Van Stones' Beautiful World Images -Hermosas World Images Van Stones
Family Modeling -modelado de la familia

WE'RE #1

WE'RE #1

Van Stones' Beautiful World Images -Hermosas World Images Van Stones

Van Stones' Beautiful World Images -Hermosas World Images Van Stones
Family Modeling -modelado de la familia

Van Stones' Beautiful Tween Images-Hermosas Imágenes Tween Van Stones

Van Stones' Beautiful Tween Images-Hermosas Imágenes Tween Van Stones
Family Modeling -modelado de la familia

WE'RE NO 1

WE'RE NO 1

Van Stones' Beautiful Youth Images -Van Stones imágenes hermosas de la Juventud

Van Stones' Beautiful Youth Images -Van Stones imágenes hermosas de la Juventud
Family Modeling -Modelado de la familia

WE'RE NO 1

WE'RE NO 1

Van Stones' Beautiful Child Images -Van Stones Niño hermoso Imágenes

WE'RE #1

Van Stones’ Beautiful Children Images - Van Stones imágenes hermosas Madre

Van Stones’ Beautiful Children Images - Van Stones imágenes hermosas Madre
Family Modeling -modelado de la familia

Like Us On Facebook

We"re Looking For Volunteers

News, and more about youth, education, political analyst, schools, anti-violence, social justice, grass roots democracy, ecological protection, seniors, Historic Preservation & Restoration, (Black, Latinos, Asian, Pakistani, Italian, and other)Arts, Books, Super Heroes, Trading Cards, Youth, College, and Pro Sports, Nonprofits and Real-estate.

Blog Archive

About Us

  • FPN can reach out to Representatives from your side of: The Village, The Township, or The City
  • FPN features
    Sports
    Cars
    Family Entertainment
    Neighborhood News
    Scholastic News
    Regional News
    National News
    Citywide News
    Legal News
    Alternative Green Energy Education News
    Superhero & Comic Strip News
  • Teen Stars
  • Humanitarian/Ministers/Political
  • Community Services
  • Women & Men & Kids

  • You acknowledge and agree that you may not copy, distribute, sell, resell or exploit for any commercial purposes, any portion of the Newspaper or Services. Unless otherwise expressly provided in our Newspaper, you may not copy, display or use any trademark without prior written permission of the trademark owner.

    FPN/VSP® is in no way responsible for the content of any site owned by a third party that may be listed on our Website and/or linked to our Website via hyperlink. VSP/FPN® makes no judgment or warranty with respect to the accuracy, timeliness or suitability of the content of any site to which the Website may refer and/or link, and FPN/VSP® takes no responsibility therefor. By providing access to other websites, FPN/VSP® is not endorsing the goods or services provided by any such websites or their sponsoring organizations, nor does such reference or link mean that any third party websites or their owners are endorsing FPN/VSP® or any of the Services. Such references and links are for informational purposes only and as a convenience to you.

    FPN/VSP® reserves the right at any time to modify or discontinue, temporarily or permanently, the Website and/or Services (or any part thereof) with or without notice to you. You agree that neither FPN/VSP® nor its affiliates shall be liable to you or to any third party for any modification, suspension or discontinuance of the Website and/or Services.

    You agree to indemnify and hold harmless FPN/VSP®, its subsidiaries, and affiliates, and their respective officers, directors, employees, shareholders, legal representatives, agents, successors and assigns, from and against any and all claims, actions, demands, causes of action and other proceedings arising from or concerning your use of the Services (collectively, "Claims") and to reimburse them on demand for any losses, costs, judgments, fees, fines and other expenses they incur (including attorneys' fees and litigation costs) as a result of any Claims.

    The Website is © 2009 by VSP®, or its designers. All rights reserved. Your rights with respect to use of the Website and Services are governed by the Terms and all applicable laws, including but not limited to intellectual property laws.

    Any contact information for troops overseas and/or soldiers at home provided to you by FPN/VSP® is specifically and solely for your individual use in connection with the services provide by Van Stone Productions Foundation VSP.

    FPN/VSP® soldiers contact information for any other purpose whatsoever, including, but not limited to, copying and/or storing by any means (manually, electronically, mechanically, or otherwise) not expressly authorized by FPN/VSP is strictly prohibited. Additionally, use of FPN/VSP® contact information for any solicitation or recruiting purpose, or any other private, commercial, political, or religious mailing, or any other form of communication not expressly authorized by FPN/VSP® is strictly prohibited.